Rapid improvement following anti-TNF treatment at the INR is seen. The patient is able to recognize his wife for the first time in years within minutes after treatment. Also seen is his improvement in verbal abilities following the local etanercept dose.
Individual results may vary. Continuing maintenance treatment is necessary to maintain the clinical response. Some patients do not respond. For further scientific information, please see:
- TNF-alpha modulation for treatment of Alzheimer’s disease: a 6-month pilot study. Edward Tobinick MD, H Gross MD, Alan Weinberger MD, Hart Cohen MD. MedGenMed. 2006 Apr 26;8(2):25.
- Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer’s disease. Edward Tobinick MD, H Gross MD. BMC Neurology. 2008 Jul 21;8:27.
- Rapid cognitive improvement in Alzheimer’s disease following perispinal etanercept administration.Edward Tobinick MD, H Gross MD. Journal of Neuroinflammation. 2008 Jan 9;5:2.